June 13-14, 2011: Second Annual 2-Day Workshop on "Introduction to Developing a Clinical Trial Application (CTA) for Cell-Based Therapies"

Based on a combination of lectures, practical experience and case studies, this workshop is specifically designed to enable participants to understand the process for developing a cell-based clinical trial in Canada. The workshop provides the opportunity to meet and network with other investigators who have a similar interest in the clinical translation of their research. The workshop also enables interactions with representatives from Health Canada's Biologics and Genetic Therapies Directorate. Participants from the US and Canada will gain an understanding of the manufacturing process, quality issues, release assays, and other factors associated with translating a cell-based product into the clinic for clinical evaluation.

For further information, please visit this link.

February 15, 2011: Cell Therapy Program hosted Young Presidents Organization (YPO) "Back to School Night"

The Young Presidents Organization is a global network of young chief executives, founded in 1950 in New York City. The organization includes approximately 18,000 business leaders in more than 100 countries, all with a common mission: Better Leaders Through Education and Idea Exchange. On February 15, 2011, the Cell Therapy Program hosted the Toronto chapter of the YPO at a "Back to School" night.

The evening began with a short address from Dr. Robert Bell, President and CEO of the University Health Network, and Paul Alofs, President and CEO of the Princess Margaret Hospital Foundation. YPO members and their spouses then went back to university decked in lab coats to listen to a stimulating lecture created specifically for the guests by Dr. Armand Keating. This was followed by a tour of the Philip S. Orsino Translational Laboratory and the Philip S. Orsino Cell Processing Facility, both at the Princess Margaret Hospital, and the STTARR Imaging Facility (located in the MaRS Discovery Tower and offering the latest imaging equipment such as MRI machines created specifically for imaging lab animals in the studies to measure efficacy of the treatment). Guests learned about stem cells and how they fit into the new field of Cell Therapy.

Back to School 1

Back to School 2

Back to School 3

Back to School 4

Back to School 5

January 30, 2011: Ontario Regional Center for Cell and Vector Production (CCVP) Enters Finalization

The proposal was revised for location and budget, and was submitted to CFI on January 30, 2011, with finalization expected shortly. We will enter the RFP process shortly after finalization. For more information please refer to the CCVP description in the Facilitites section.

December 13-14, 2010: Cell Therapy Program interacts with Health Canada to shape CTA guidelines.

Dr. Viswanathan and Dr. Keating, along with Dr. Denis-Claude Roy, and the Stem Cell Network hosted a two-day workshop to influence the Clinical Trial Application guidelines and process for cell based therapies.

June 19, 2009: New CFI Funding Announced for UHN

In a press conference held at the University of Ottawa yesterday, the Canada Foundation for Innovation (CFI) announced funding to three UHN-led projects totaling $15.4M in new infrastructure support.

Dr. Armand Keating will receive $7.3M in infrastructure support under the Leading Edge Fund (LEF) to establish the "Ontario Regional Center for Cell and Vector Production". This regional initiative will service a full spectrum of therapeutic cell and gene research, including regenerative medicine, cancer and immune dysregulation (e.g. graft-versus-host disease, autoimmune disorders).

Under the New Initiatives Fund (NIF), Dr. David Jaffray was awarded $5.5M for his project entitled "Robotic Positioning for Image-Guided Surgery and Radiation Therapy"--to build two translational research environments that use intra-operative and robotic systems for highly conformal, localized and minimally invasive radiation therapy.

Also under the NIF program, $2.4M will be provided to Dr. Gang Zheng and his team to establish the "NanoMed Fab: A Nanofabrication Centre for Personalized Medicine". This project will implement emerging concepts in nanotechnology, molecular engineering and medicine in designing targeted nanoparticles that can be seamlessly translated and tested into clinical settings.

A total of $247.6M was awarded to 64 projects under the LEF program and $264.7M was awarded to 69 projects under the NIF program.