About Philip S. Orsino Cell Therapy Facility

In order to implement cell-based therapies in a clinical setting, a facility is required to safely undertake the complex manipulation required for cells destined for human use. The Philip S. Orsino Cell Therapy Facility is a state-of-the-art facility offering Good Manufacturing Practice (GMP) grade cell and tissue processing capabilities. The facility is the result of a joint funding effort between the Canada Foundation for Innovation, the Ontario Innovation Trust, and the generosity of philanthropist Philip S. Orsino.

The Orsino facility provides the necessary infrastructure and support for the implementation of clinical-scale cell manufacturing. Areas of expertise include development of robust and reproducible standard operating procedures, scale-up and optimization.

The facility serves multiple purposes:
  • To support novel cell therapy research at University Health Network by providing GMP grade cell processing for investigator-initiated trials
  • To service the needs of the Blood and Marrow Transplant Program at Princess Margaret Hospital
  • To provide a full array of manufacturing and consulting services to external commercial and academic partners